2016;68(4):1026-1073. doi:10.1124/pr.115.010843. While milk thistle has been traditionally used in pregnant and breastfeeding women, its safety is unknown. Milk thistle may change the way your liver metabolizes certain drugs, like blood thinners, antibiotics, and anti-inflammatory medications. 2020 Feb;47(2):302-312. doi: 10.1111/1440-1681.13201. Advertising revenue supports our not-for-profit mission. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: A randomized, triple-blind, placebo-controlled clinical trial, By Soraiya Ebrahimpour Koujan, Bahram Pourghassem, Gargari Majid, Published February 15, 2015, Retrieved May 5, 2019, 8. https://www.ncbi.nlm.nih.gov/pubmed/28025940, Current Drug Targets, A Mini Review on the Chemistry and Neuroprotective Effects of Silymarin, By Devi KP, Malar , Braidy , Nabavi , Nabavi, Published 2017, Retrieved May 5, 2019, 9. https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+1964, Toxnet, Valerian Root, Reviewed by SRP on 9/9/2014, Retrieved May 5, 2019, 10. https://nccih.nih.gov/research/results/spotlight/040310.htm, National Center for Complementary and Integrative Health, Study Shows Chamomile Capsules Ease Anxiety Symptoms, Last Updated October 21, 2015, Retrieved May 5, 2019, 11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612440/, Evidence Based Complementary Medicine, Lavender and The Nervous System, Published March 14, 2013, By Peir Hossein Koulivand, Maryam Khaleghi Ghadiri, and Ali Gorji, Retrieved May 5, 2019, 12. https://www.webmd.com/vitamins/ai/ingredientmono-437/lemon-balm, WebMD.com, Lemon Balm, Retrieved May 5, 2019, Requirements for using and reposting articles. Milk thistle and its antioxidant properties are promising in managing OCD symptoms but it may also be beneficial to explore other herbs for OCD treatment to bolster and round out a supplement regimen. Accessed Oct. 30, 2020. Minerals for OCD Milk thistle may not be safe for everyone. Unexpected effects from milk thistle. And although milk thistle extract is commonly used as a complementary therapy for people with liver diseases, theres currently no evidence that it can prevent you from getting these conditions, especially if you have an unhealthy lifestyle. And, most recently, milk thistle is gaining traction as a natural remedy to help manage the symptoms of OCD. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. Summary Milk thistle extract may help protect the liver against damage caused by disease or poisoning, though more research is needed. 2005 - 2023 WebMD LLC, an Internet Brands company. Silibinin, a flavonoid derived from milk thistle (Silybum marianum), has been used as a hepato-protectant in the clinical treatment of liver diseases. Bunchorntavakul C, Wootthananont T, Atsawarungruangkit A. For guidance from NCCIH on using PubMed, see How To Find Information About Complementary Health Approaches on PubMed. Find out more on the side effects of statins. Questions? In trying to determine the proper milk thistle OCD dosage, herbalists and experts tend to recommend 200-400mg divided across two or three doses per day (5). Studies have shown a decrease in blood sugar levels and an improvement in cholesterol in. Large-scale, properly-designed studies are needed. Song X, Zhou B, Cui L, Lei D, Zhang P, Yao G, Xia M, Hayashi T, Hattori S, Ushiki-Kaku Y, Tashiro SI, Onodera S, Ikejima T. Neurochem Res. The benefits of milk thistle remain unclear for this purpose and the limited research on milk thistle and breast milk has been done primarily in animals. Milk thistle may interact with certain medications and supplements. National Library of Medicine (US); 2022. Dosing of milk thistle ranged from 150 mg twice a day to 300 mg twice a day. Depression is one of the most frequent psychiatric disorders of Alzheimer's disease (AD). Milk thistle is taken by mouth most often for liver disorders, including liver damage caused by chemicals, alcohol, and chemotherapy, as well as liver damage caused by Amanita phalloides (death cap) mushroom poisoning, jaundice, chronic inflammatory liver disease, cirrhosis of the liver, and chronic hepatitis. Adv Ther. Do not use extra milk thistle to make up the missed dose. Pizzorono JE, et al., eds. https://www.nccih.nih.gov/health/milk-thistle. Other studies looking at milk thistle for cirrhosis have found conflicting results. Here are 10 of the best herbs for your liver, including benefits and. Summary In animals, milk thistle has been shown to stimulate bone mineralization. Malaria. Song X, Zhou B, Zhang P, Lei D, Wang Y, Yao G, Hayashi T, Xia M, Tashiro S, Onodera S, Ikejima T. Neurochem Res. Medical research suggests that milk thistle, combined with traditional treatment, can improve diabetes. 2008;47(2):605-12. doi:10.1002/hep.22044, Fried MW, Navarro VJ, Afdhal N, et al. Liu HY, Wei HJ, Wu L, Liu SM, Tang YY, Zou W, Wang CY, Zhang P, Tang XQ. Milk thistle is not recommended for children. Milk Thistle Tea: Benefits, Side Effects, and Dosage - Healthline https://naturalmedicines.therapeuticresearch.com. The Physician Global Assessment and Body Surface Area composite tool is a simple alternative to the Psoriasis Area and Severity Index for assessment of psoriasis: post hoc analysis from PRISTINE and PRESTA. Theres conflicting research on the benefits of milk thistle for liver health. 2014;97 Suppl 11:S31-S40. Before Results from clinical trials of milk thistle for liver diseases have been conflicting or havent been clinically meaningful. Research Breakdown on Milk Thistle - Examine This prickly plant has distinctive purple flowers and white veins, which traditional stories say were caused by a drop of the Virgin Marys milk falling onto its leaves. However, there are currently no human studies examining the effects of milk thistle in people with Alzheimers or other neurological conditions like dementia and Parkinsons. It can help prevent elevation of liver enzymes, which can be a side effect of the medication. Milk Thistle Health Benefits: Antioxidant and Anti-inflammatory 5 It was found that there was no significant difference between milk thistle and Prozac for OCD symptoms. J Med Assoc Thai. 2014;11(2):167-74. doi:10.1900/RDS.2014.11.167, Rambaldi A, Jacobs BP, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. Int J Mol Sci. Effect of silymarin on biochemical indicators in patients with liver disease: systematic review with meta-analysis. Wanting to take Milk Thistle and Curcumin to alleviate OCD, Depression It's also proven useful in treating skin that's been damaged by radiation during breast cancer treatment. Historically, people have used milk thistle for liver disorders and gallbladder problems. What Are the Risks of Taking Milk Thistle? Careers. As a result of excessive alcohol consumption, my liver was fattened and my enzymes increased.
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